The Ultimate Guide to the Best Supplements for Muscle Growth

When it comes to building muscle, the right combination of exercise, nutrition, and supplements can make a significant difference. Supplements are designed to fill nutritional gaps, enhance performance, and speed up recovery, making them essential for anyone serious about muscle growth.

In this guide, we'll explore the best supplements for muscle growth and how they can help you achieve your fitness goals.

Top Supplements for Muscle Growth

If you want to maximize muscle growth and strength, consider adding one or more of these supplements into your routine...

1. Protein Powder

Protein is the building block of muscle tissue. Consuming sufficient protein is essential for muscle repair and growth. Protein powders, such as whey, casein, and plant-based proteins, provide a convenient and effective way to increase protein intake.


  • Promotes muscle repair and growth.
  • Convenient and easy to consume.
  • Helps meet daily protein requirements.
  • Helps you feel food which can aid in fat loss (for those with weight loss goals).

Recommended Dosage: Consume 20-30 grams of protein powder post-workout or as needed to meet your daily protein goals. Whey protein is ideal for post-workout due to its fast absorption, while casein is better suited for nighttime due to its slow digestion rate.

Types of Protein Powder:

  • Whey Protein: Fast-absorbing, complete protein with all essential amino acids.
  • Casein Protein: Slow-digesting, ideal for nighttime recovery.
  • Plant-Based Proteins: Options like pea, hemp, and brown rice protein for those with dietary restrictions.

2. Creatine Monohydrate

Creatine increases the availability of ATP (adenosine triphosphate), the primary energy currency of cells. This enhances your ability to perform high-intensity exercises, leading to greater strength and muscle gains.


  • Increases strength and power.
  • Enhances muscle volume and cell hydration.
  • Supports muscle recovery and reduces muscle fatigue.
  • Promotes lean muscle mass gains.

Recommended Dosage: Take 3-5 grams of creatine monohydrate daily. Many people start with a loading phase of 20 grams per day for the first 5-7 days, then switch to a maintenance dose.

Additional Tips:

  • Loading Phase: Can help saturate muscles faster, but it's not mandatory.
  • Hydration: Ensure adequate water intake to prevent dehydration and enhance creatine’s effectiveness.

3. Branched-Chain Amino Acids (BCAAs)

BCAAs (leucine, isoleucine, and valine) are essential amino acids that stimulate muscle protein synthesis and reduce muscle breakdown. Leucine, in particular, plays a crucial role in initiating muscle protein synthesis.


  • Enhances muscle recovery.
  • Reduces muscle soreness (DOMS).
  • Supports muscle protein synthesis.
  • Provides energy during workouts, reducing fatigue.

Recommended Dosage: Consume 5-10 grams of BCAAs before, during, or after workouts. The ideal ratio of leucine to isoleucine and valine is 2:1:1.

Additional Tips:

  • Intra-Workout: Drinking BCAAs during workouts can help maintain muscle mass during intense training sessions.

4. Beta-Alanine

Beta-alanine is an amino acid that increases muscle carnosine levels, which helps buffer acid in muscles, reducing fatigue and enhancing performance. This buffering effect allows you to perform more reps at a given weight, contributing to greater muscle growth over time.


  • Improves exercise performance and endurance.
  • Delays muscle fatigue.
  • Increases workout intensity and volume.
  • Enhances muscular endurance, particularly during high-intensity interval training (HIIT).

Recommended Dosage: Take 2-5 grams of beta-alanine daily, ideally split into multiple doses to avoid tingling sensations (paresthesia).

Additional Tips:

  • Paresthesia: The tingling sensation is harmless but can be minimized by splitting doses throughout the day.
  • Combination: Often included in pre-workout supplements for its performance-enhancing benefits.

5. L-Glutamine

Glutamine is the most abundant amino acid in the body and plays a crucial role in muscle recovery, immune function, and gut health. It helps replenish glycogen stores after exercise, supporting muscle recovery and growth.


  • Enhances muscle recovery and reduces muscle soreness.
  • Supports immune health.
  • Promotes gut health, which is vital for nutrient absorption.
  • Helps maintain muscle mass during intense training or calorie deficits.

Recommended Dosage: Consume 5-10 grams of glutamine post-workout or before bed.

Additional Tips:

  • Post-Workout: Helps replenish glutamine levels depleted during intense exercise.
  • Gut Health: Beneficial for individuals with gut health issues, as it supports the integrity of the gut lining.

Combining Supplements for Maximum Muscle Growth

To get the best results, it's essential to use these supplements in conjunction with a well-rounded diet and a consistent workout routine.

Here’s an example of how you can combine the supplements listed above:

  1. Morning: Take 3-5 grams of creatine monohydrate with breakfast.
  2. Pre-Workout: Consume 5-10 grams of BCAAs and 2-5 grams of beta-alanine.
  3. Post-Workout: Have a protein shake with 20-30 grams of whey protein and 5 grams of glutamine.

You can take them depending on your preferences. For example, some like to combine creatine with pre-workout while others like to take it at a specific time every day. So, it comes down to a matter of personal preference.

Frequently Asked Questions (FAQs)

Are supplements necessary for muscle growth?

While supplements can enhance muscle growth, they are not absolutely necessary.

A balanced diet rich in protein, adequate calories, and a proper workout routine can also support muscle growth. However, supplements can provide a convenient way to meet nutritional needs and boost performance.

Can I take multiple supplements at once?

Yes, many supplements can be taken together safely.

For example, combining protein powder, creatine, and BCAAs can provide comprehensive support for muscle growth. However, it's essential to follow recommended dosages.

How long does it take to see results from muscle growth supplements?

The time it takes to see results can vary depending on factors such as diet, exercise routine, and individual response. Generally, you may start to notice improvements in strength and muscle size within a few weeks to a couple of months of consistent supplement use.

Where can I find the best supplements for muscle growth with no unnecessary fillers?

Look no further than 373 Lab!

At 373 Lab, we create high-quality supplements with fewer fillers to enhance your training, muscle mass and strength, and recovery.

For muscle growth, check out our widely loved Whey Protein Isolate with high protein content + naturally flavored to perfection, our Micronized Creatine Monohydrate which is designed for maximum absorption and effectiveness, and BCAA's in an an ideal 2:1:1 ratio of L-Leucine, L-Isoleucine, and L-Valine.

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